Spanish La Liga is a unique league with 3 favourites whose knockout from the top 4 is almost impossible. Who will win the championship with Messi out for Barca? Let’s look at the latest La Liga 2021-22 betting odds for the winner, top 4, relegation and top goalscorers.

To win 2021-22 La Liga betting market: latest odds, statistics and probabilities

Real Madrid, the most titled club in the history of La Liga, has won the championship 3 times in the last 10 years and have finished in the top 3 in almost all the past seasons.

Los Blancos came close to winning last season, but took second place only being 4 points behind the new champions, Atletico Madrid. We saw 25 wins, 9 draws and 4 losses for them in the 2020-21 La Liga. Real Madrid also came close to making it to the Champions League final last time, but they were knocked out by Chelsea, who later won the tournament

This summer Madrid have been reinforced by centre-back David Alaba, who will replace ex-club captain Sergio Ramos. Also, many players returned from their loans in various clubs.

Last season Los Blancos’ squad was in good shape, and they have every chance to celebrate a victory this time around. Real Madrid to win 2021-22 La Liga are priced with the odds of 2.50 (+150 American; 3/2 Fractional), whereas their finish in the top 4 comes with the odds of 1.07 (-1400; 1/14).

Barcelona have been runners-up the most times in La Liga. They have won 5 of the last 10 seasons, the most in the league, and have remained in the top 3 for the rest.

Barcelona finished last season third for the first time in 14 seasons. Blaugrana won 24 matches, drew 7 and lost the exact same number of games. Their performance in the Champions League was disappointing too. They lost in Round of 16 to Paris Saint-Germain after 1-4 thrashing in the first leg at Camp Nou.

Barcelona have added 4 top players to their roster this summer: Sergio Aguero, Memphis Depay, Emerson Royal and Eric Garcia. Despite the fact that some of the best forwards have joined Blaugrana for the next season, it is unlikely that they will compensate for the loss of Lionel Messi.

Barcelona to win the 27th season of La Liga are priced with the odds of 3.25 (+225; 9/4). Blaugrana to finish in the top 4 come with the odds of 1.25 (-400; 1/4).

Atletico Madrid are the current champions of La Liga. They have the most third places in the history of the league as they have long been overshadowed by Barcelona and Real Madrid. The Colchoneros have won 2 seasons in the last 10 years.

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The 2020-21 season of La Liga ended with 26 wins, 8 draws and only 4 losses for them. Their Champions League result last season was just as bad as Barcelona’s: they were knocked out in the Round of 16, losing to Chelsea.

Atletico Madrid haven’t had an active transfer summer. The Colchoneros have acquired Rodrigo de Paul, who is supposed to strengthen the club’s defensive link.

Atletico Madrid to win the second La Liga season in a row are priced with the odds of 4.50 (+350; 7/2), whereas their finish in the top 4 comes with the odds of 1.25 (-400; 1/4).

To finish 2021-22 La Liga in top 4 betting market: latest odds, statistics and probabilities

Sevilla are significantly weaker than the above-listed clubs, but they are the most likely contender for the 4th place after them. They have finished like this the last couple of times.

In the previous season, Los Hispalanses showed an exceptional run of form: they lacked only 2 points to break into the invincible top 3, while the difference between them and the fifth place was huge — 15 points. They won 24 matches, drew 5 and lost 9 games.

Sevilla was close to pulling off a surprise in the Champions League too, losing in the Round of 16 to Borussia Dortmund with a 2-2 draw in the away leg and 2-3 defeat at home.

This summer, 2 free agents have entered the camp of Sevilla: Marko Dmitrovic and Erik Lamela. However, it is unlikely that they will have a significant effect on the squad.

Sevilla to finish in the top 4 come with the odds of 2.20 (+120; 6/5). At the same time, you can bet on Sevilla to win 2021-22 La Liga with the odds of 21.00 (+2000; 20/1).

Two clubs are close to Sevilla by chances to finish 4th or higher in the league: Real Sociedad — 3.25 (+225; 9/4) and Villarreal — 3.50 (+250; 5/2).

To be relegated from 2021-22 La Liga betting market: latest odds, statistics and probabilities

Rayo Vallecano are the main contenders to be eliminated from the league. Los Vallecanos were lucky enough to make it to La Liga, finishing the Segunda Division in 6th place. Last season they won 19 matches, drew 10 times and lost the remaining 13 games.

Last time their performance in La Liga brought Vallecano the last place. During that season, they won 8 matches only, and it took them 2 seasons to return to the Primera Division.

Rayo Vallecano to finish the 2021-22 La Liga last are priced with the odds of 2.00 (+100; 1/1). Odds for them to be eliminated are equal to 1.10 (-1000; 1/10).

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Espanyol headed the 2020-21 Segunda Division, which allowed the club to return to La Liga Primera. The Periquitos finished the previous season with 24 wins, 10 draws and 8 losses.

Regardless, their last performance in La Liga makes them the second contenders for relegation this season. The 2019-20 La Liga ended with 5 wins, 10 draws and 23 losses for Espanyol — and the last place (25 points).

Espanyol to finish this season at the bottom come with the odds of 2.25 (+125; 5/4), whereas their relegation is priced with the odds of 1.20 (-500; 1/5).

Top 2021-22 La Liga goalscorer betting market: latest odds, statistics and probabilities

Karim Benzema was the second best striker in the 2020-21 season of La Liga. Benzema scored 23 goals and made 8 assists in the 2020-21 La Liga season. Only Lionel Messi topped him, but the Argentine has moved to PSG this summer, so the Frenchman has everything to become the best this time.

Karim also scored 4 goals in 4 matches for the French national team at the Euro 2020, which is the best result among the players of his country. Benzema to score the greatest number of goals in this La Liga season is priced with the odds of 4.50 (+350; 7/2).

Memphis Depay was the second top scorer in 2020-21 Ligue 1. The Dutch striker scored 20 goals and 12 assists in 37 Ligue 1 games. He also created 94 chances in penalty areas, more than double that of his main rival, Karim Benzema.

Now Depay has left Lyon and has joined Barcelona. Memphis Depay to be the top goalscorer in his debut season in La Liga comes with the odds of 8.00 (+700; 7/1).

The new La Liga season will kick off on Friday, August 13.